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Associate Director, Drug Metabolism and Pharmacokinetics

April 30, 2026

At Insmed, every moment and every patient counts — and so does every person who joins in. As a global biopharmaceutical company dedicated to transforming the lives of patients with serious and rare diseases, you’ll be part of a community that prioritizes the human experience, celebrates curiosity, and values every person’s contributions to meaningful progress. That commitment has earned us recognition as Science magazine’s No. 1 Top Employer for five consecutive years, certification as a Great Place to Work® in the U.S., and a place on The Sunday Times Best Places to Work list in the UK.For patients, for each other, and for the future of science, we’re in. Are you?About the Role:The Associate Director DMPK will be accountable for the non-clinical pharmacokinetics and drug metabolism components of drug discovery and development programs at Insmed, including small and large molecules. The Associate Director DMPK is expected to have in-depth DMPK knowledge and hands-on experience, and be familiar with pharmaceutical drug discovery and development. This role will work collaboratively with other team members and provide oversight of vendors.What You'll Do: <ul><li>Serve as a DMPK lead on assigned project teams, responsible for strategy and execution of non-clinical drug metabolism programs for small and large molecules in Discovery and Development.</li><li>Participate in the design, data analysis and interpretation of DMPK and non-clinical PK/PD studies.</li></ul><ul><li>Support TK study design and data interpretation.</li><li>Author DMPK sections of regulatory submissions such as briefing books, INDs, CTAs and NDAs.</li><li>Provide CRO oversight for in vitro and in vivo DMPK studies.</li><li>Work with in-house laboratory to expand DMPK capabilities.</li><li>Closely partner with Research, Toxicology, Clinical Development, Regulatory, Project Management, and other functions.</li></ul><ul><li>Participate in the design, data analysis and interpretation of DMPK and non-clinical PK/PD studies.</li></ul>Who You Are:<ul><li>PhD in pharmacokinetics, pharmaceutical sciences or related scientific discipline with a minimum of 8 years of biotech/pharmaceutical drug discovery and development experience.</li><li>Expertise with in vitro and in vivo DMPK studies.</li><li>Previous involvement in both drug Discovery and drug Development programs is a plus.</li><li>Experience vetting and collaborating with CROs on a wide range of studies.</li><li>Ability to plan, organize, and critically assess and perform PK/PD data analyses..</li><li>Experience preparing DMPK sections of regulatory submissions.</li><li>Excellent oral and written communication skills.</li><li>Problem solving and critical thinking skills are essential.</li></ul>Nice to have (but not required):<ul><li>Familiarity in development of protein therapeutics, antisense oligonucleotides and/or gene therapies is a plus.</li><li>Hands-on experience with Phoenix WinNonlin, NONMEM, R and/or ADME prediction software is a plus.</li></ul>Where You’ll Work:This is a fully remote role. It can be performed effectively from anywhere while staying connected to your Insmed team and community. Occasional travel for team meetings or events will be expected. Travel Requirements:This role requires occasional [domestic/international/global] travel (approximately [5%–15%])Pay Range:$164,000.00-213,000.00 AnnualLife at Insmed At Insmed, you’ll find a culture as human as our mission—intentionally designed for the people behind it. You deserve a workplace that reflects the same care you bring to your work each day, with support for how you work, how you grow, and how you show up for patients, your team, and yourself.Highlights of our U.S. offerings include:<ul><li>Comprehensive medical, dental, and vision coverage and mental health support, annual wellbeing reimbursement, and access to our Employee Assistance Program (EAP)</li><li>Generous paid time off policies, fertility and family-forming benefits, caregiver support, and flexible work schedules with purposeful in-person collaboration</li><li>401(k) plan with a competitive company match, annual equity awards, and participation in our Employee Stock Purchase Plan (ESPP), and company-paid life and disability insurance</li><li>Company Learning Institute providing access to LinkedIn Learning, skill building workshops, leadership programs, mentorship connections, and networking opportunities</li><li>Employee resource groups, service and recognition programs, and meaningful opportunities to connect, volunteer, and give back</li></ul>Eligibility for specific programs may vary and is subject to the terms and conditions of each plan. Current Insmed Employees: Please apply via the Jobs Hub in Workday.<h3></h3>Insmed Incorporated is an Equal Opportunity employer. We do not discriminate in hiring on the basis of physical or mental disability, protected veteran status, or any other characteristic protected by federal, state, or local law. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. Unsolicited resumes from agencies should not be forwarded to Insmed. Insmed will not be responsible for any fees arising from the use of resumes through this source. Insmed will only pay a fee to agencies if a formal agreement between Insmed and the agency has been established. The Human Resources department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement. Insmed is committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, its services, programs, and activities. To request reasonable accommodation to participate in the job application or interview process, please contact us by email at <a href="mailto:TotalRewards@insmed.com" target="_blank" rel="noopener noreferrer">TotalRewards@insmed.com</a> and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address. Applications are accepted for 5 calendar days from the date posted or until the position is filled.For New York City Residents:To assist in identifying candidates with qualifications matching those required and/or preferred for this role, Insmed uses an Automated Employment Decision Tool (“AEDT”) that employs artificial intelligence to analyze and score information provided in resumes and application materials including, but not limited to, skills, work experience, education, and job-related qualifications. The AEDT does not make final hiring decisions and all final hiring decisions are subject to human oversight and/or review. If you are an applicant for this role and a New York City resident, you have the right to request: <ul><li>A reasonable accommodation, if one is available under applicable law, by emailing <a href="mailto:TotalRewards@insmed.com" target="_blank" rel="noopener noreferrer">TotalRewards@insmed.com</a>; and/or</li><li>An alternative selection process by emailing <a href="mailto:Privacy@insmed.com" target="_blank" rel="noopener noreferrer">Privacy@insmed.com</a>.</li><li>Information about the type of data collected, the source of that data, and data retention practices related to the AEDT by emailing us at <a href="mailto:Privacy@insmed.com" target="_blank" rel="noopener noreferrer">Privacy@insmed.com</a>.</li></ul>

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Common Interview Questions And Answers

1. HOW DO YOU PLAN YOUR DAY?

This is what this question poses: When do you focus and start working seriously? What are the hours you work optimally? Are you a night owl? A morning bird? Remote teams can be made up of people working on different shifts and around the world, so you won't necessarily be stuck in the 9-5 schedule if it's not for you...

2. HOW DO YOU USE THE DIFFERENT COMMUNICATION TOOLS IN DIFFERENT SITUATIONS?

When you're working on a remote team, there's no way to chat in the hallway between meetings or catch up on the latest project during an office carpool. Therefore, virtual communication will be absolutely essential to get your work done...

3. WHAT IS "WORKING REMOTE" REALLY FOR YOU?

Many people want to work remotely because of the flexibility it allows. You can work anywhere and at any time of the day...

4. WHAT DO YOU NEED IN YOUR PHYSICAL WORKSPACE TO SUCCEED IN YOUR WORK?

With this question, companies are looking to see what equipment they may need to provide you with and to verify how aware you are of what remote working could mean for you physically and logistically...

5. HOW DO YOU PROCESS INFORMATION?

Several years ago, I was working in a team to plan a big event. My supervisor made us all work as a team before the big day. One of our activities has been to find out how each of us processes information...

6. HOW DO YOU MANAGE THE CALENDAR AND THE PROGRAM? WHICH APPLICATIONS / SYSTEM DO YOU USE?

Or you may receive even more specific questions, such as: What's on your calendar? Do you plan blocks of time to do certain types of work? Do you have an open calendar that everyone can see?...

7. HOW DO YOU ORGANIZE FILES, LINKS, AND TABS ON YOUR COMPUTER?

Just like your schedule, how you track files and other information is very important. After all, everything is digital!...

8. HOW TO PRIORITIZE WORK?

The day I watched Marie Forleo's film separating the important from the urgent, my life changed. Not all remote jobs start fast, but most of them are...

9. HOW DO YOU PREPARE FOR A MEETING AND PREPARE A MEETING? WHAT DO YOU SEE HAPPENING DURING THE MEETING?

Just as communication is essential when working remotely, so is organization. Because you won't have those opportunities in the elevator or a casual conversation in the lunchroom, you should take advantage of the little time you have in a video or phone conference...

10. HOW DO YOU USE TECHNOLOGY ON A DAILY BASIS, IN YOUR WORK AND FOR YOUR PLEASURE?

This is a great question because it shows your comfort level with technology, which is very important for a remote worker because you will be working with technology over time...